Refereed Journal Articles

  1. Grisell Caridad Gonzalez, Chris Michael Li, Ilaria Pasolini, Sophia Irene Pete, Connor Verheyen, Sofia M Vignolo, Teresa De Toni, Aaron Andrew Stock, Alice Anna Tomei, High-yield Generation of Glucose-responsive Pseudoislets from Murine Insulinoma Cells for In vitro Studies and Longitudinal Monitoring of Graft Survival In Vivo; Cell Transplantation (IF: 3.2), Special Collection on Cellular Replacement Therapy for Diabetes, 2025 Jan-Dec;34:9636897251315123. doi:10.1177/09636897251315123. PMID: 39881520 https://pubmed.ncbi.nlm.nih.gov/39881520/
  2. Grattoni A, Korbutt G, Tomei AA, García AJ, Pepper AR, Stabler CL, Brehm M, Papas K, Citro A, Shirwan H, Millman J, Melero-Martin J, Graham M, Sefton M, Ma M, Kenyon N, Veiseh O, Desai TA, Nostro MC, Marinac M, Sykes M, Russ HA, Odorico J, Tang Q, Mamrak NE, Giraldo J, Poznansky MC, de Vos P, Harnessing Cellular Therapeutics for Type 1 Diabetes: Progress, Challenges, and the Road Ahead, Nature Reviews Endocrinology (IF: 40.5) 2024 https://doi.org/10.1038/s41574-024-01029-0 https://pubmed.ncbi.nlm.nih.gov/39227741/
  3. De Toni T, Dal Buono T, Li CM, Gonzalez GC, Chuang ST, Buchwald P, Tomei AA, Velluto D. Drug Integrating Amphiphilic Nano-Assemblies: 2. Spatiotemporal Distribution within Inflammation Sites. Pharmaceutics (IF: 5.4). 2024 May 13;16(5):652. doi: 10.3390/pharmaceutics16050652. PMID: 38794314; PMCID: PMC11124943. https://pubmed.ncbi.nlm.nih.gov/38794314/
  4. Berishvili E, Peloso A, Tomei AA, Pepper AR. The Future of Beta Cells Replacement in the Era of Regenerative Medicine and Organ Bioengineering. Transpl Int. (IF: 3.1) 2024 Mar 13;37:12885. doi: 10.3389/ti.2024.12885. PMID: 38544564; PMCID: PMC10966588. https://pubmed.ncbi.nlm.nih.gov/38544564/
  5. Asthana A, Chaimov D, Tamburrini R, Gazia C, Gallego A, Lozano T, Heo JH, Byers L, Tomei A, Fraker C, Walker S, Lee S, Opara E, Orlando G, Decellularized human pancreatic extracellular matrix-based physiomimetic microenvironment for human islet culture; Acta Biomater. (IF: 9.7) 2023 Nov;171:261-272. doi: 10.1016/j.actbio.2023.09.034. Epub 2023 Sep 22 
  6. Xi Wang, Kai Wang, Ming Yu, Diana Velluto, Xuechong Hong, Bo Wang, Alan Chiu, Juan M. Melero-Martin, Alice A. Tomei, Minglin Ma, Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression; Science Advances (IF: 14.136) 2022 Jul 22;8(29):eabn0071.doi: 10.1126/sciadv.abn0071. Epub 2022 Jul 22 https://pubmed.ncbi.nlm.nih.gov/35867788/
  7. Stock AA, Gonzalez GC, Pete SI, De Toni T, Berman DM, Rabassa A, Diaz W, Geary JC Jr, Willman M, Jackson JM, DeHaseth NH, Ziebarth NM, Hogan AR, Ricordi C, Kenyon NS, Tomei AA, Performance of islets of Langerhans conformally coated via an emulsion cross-linking method in diabetic rodents and nonhuman primates; Sci Adv. (IF: 14.136) 2022 Jul; 8(26):eabm3145. doi: 10.1126/sciadv.abm3145. Epub 2022 Jun 29 https://pubmed.ncbi.nlm.nih.gov/35767620/
  8. Zisi Tegou F, Velluto D, Stock AA, Fitzgerald SN, Stealey S, Zustiak SP, Bayer AL, Tomei AA, CCL21 and beta-cell antigen releasing hydrogels as tolerance-inducing therapy in Type I diabetes; Journal of Controlled Release (IF: 11.47). 2022 Jun 16;348:499-517. doi: 10.1016/j.jconrel.2022.06.008. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35691500/
  9. De Toni T, Stock AA, Devaux F, Gonzalez GC, Nunez K, Rubanich JC, Safley SA, Weber CJ, Ziebarth NM, Buchwald P, Tomei AA, Parallel Evaluation of Polyethylene Glycol Conformal Coating and Alginate Encapsulation as Immunoisolation Strategies for Pancreatic Islet Transplantation; Front Bioeng Biotechnol (IF: 6.064). 2022 May 16;10:886483. doi: 10.3389/fbioe.2022.886483.eCollection 2022. https://pubmed.ncbi.nlm.nih.gov/35651551/
  10. Diana Velluto, Damir Bojadzic, Teresa De Toni, Peter Buchwald, Alice A. Tomei, Drug-integrating amphiphilic nanomaterial assemblies: 1. Spatiotemporal control of cyclosporine delivery and activity using nanomicelles and nanofibrils, Journal of Controlled Release (IF: 11.47) 2021 Jan 10;329:955-970. doi: 10.1016/j.jconrel.2020.10.026. Epub 2020 Oct 18. https://pubmed.ncbi.nlm.nih.gov/33086102/
  11. ASTHANA, A.; Riccardo Tamburrini; Deborah Chaimov; Stephen J Walker; Mark Van Dyke; Tomei AA; Sandrine Lablanche; Emmanuel Opara; Shay Soker, Giuseppe Orlando, Comprehensive characterization of the human pancreatic proteome for bioengineering applications, Biomaterials (F:12.49), 2021 Mar;270:120613. doi: 10.1016/j.biomaterials.2020.120613. Epub 2020 Dec 16
  12. Riccardo Tamburrini, Deborah Chaimov, Kevin Enck, Sean M. Muir, Amish Asthana,Justine Mariam Aziz, Sandrine Lablanche,  Emily Tubbs, Tomei AA, Mark Van Dyke, Shay Soker, Emmanuel C Opara, Orlando G, Detergent Free Protocol for the Decellularization of the Human Pancreas for the Production of a Soluble Extracellular Matrix (ECM), J Vis Exp. (IF: 1.2) 2020 Sep 4;(163). doi:10.3791/61663.PMID: 32955501 (IF: 1.325). https://pubmed.ncbi.nlm.nih.gov/32955501/
  13. Susan A. Safley, Norma S. Kenyon, Dora M. Berman, Graham F. Barber, Hong Cui, Stephanie Duncanson, Teresa De Toni,  Melissa Willman,  Paul de Vos, Alice A Tomei, Athanassios Sambanis, Camillo Ricordi, Collin J. Weber, Microencapsulated Islet Allografts in Diabetic NOD Mice and Nonhuman Primates, European Review for Medical and Pharmacological Sciences (IF: 1.575) 2020, Aug;24 (16): 8551-8565 https://pubmed.ncbi.nlm.nih.gov/32894560/
  14. Freddy Gonzalez Badillo, Flavia Zisi Tegou, Riccardo Masina, Shane Wright, Mackenzie Scully, Laura Harwell, Mike Lupp, Jorge Postigo-Fernandez, Remi J. Creusot, Tomei AA, Tissue-Engineered Stromal Reticula to Study Lymph Node Fibroblastic Reticular Cells in Type I Diabetes, Cellular and Molecular Bioengineering (CMBE) (IF: 2.5) 2020, special Young Innovator Award, 13, Jun 26;13(5):419-434 https://pubmed.ncbi.nlm.nih.gov/33184575/
  15. Sibilla S, Manenti S, Cazzato T, Colombo F, Tomei AA, Redaelli A, Manzoli V, Consolo F, SPH multiphase modelling of an experimental microfluidic device for conformal coating of pancreatic islets, Medical Engineering and Physics (IF: 1.923), 2020 Mar; 77:19-30. https://pubmed.ncbi.nlm.nih.gov/32008936/
  16. Stock AA, Manzoli V, De Toni T, Abreu MM, Poh YC, Ye L, Roose A, Pagliuca FW, Thanos C, Ricordi C and Tomei AA, Conformal Coating of Stem Cell-Derived Islets for Beta Cell Replacement in Type 1 Diabetes, Stem Cell Report (IF: 6.5) 2020 Jan 14; 14 (1), 91-104 https://pubmed.ncbi.nlm.nih.gov/31839542/
  17. Gonzalez-Badillo F, Zisi Tegou F, Abreu MM, Masina R, Sha D, Najjar M, Wright S, Bayer AL, Korpos E, Pugliese A, Molano RD, Tomei AA, CCL21 Expression in Beta Cells Induces Fibroblastic Reticular Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice, Diabetes (IF: 7.273); Coverart awarded. 2019 Oct; 68(10): 1990-2003. https://pubmed.ncbi.nlm.nih.gov/31371518/
  18. Verheyen CA, Morales L, Sussman J, Paunovska K, Manzoli V, Ziebarth NM, Tomei AA, Characterization of Polyethylene Glycol-Reinforced Alginate Microcapsules for Mechanically Stable Cell Immunoisolation, Macromolecular Materials and Engineering (IF: 2.781); 2019: 304 (4): 1800679. https://pubmed.ncbi.nlm.nih.gov/31929732/
  19. Tomei AA, Engineering Confined and Pre-vascularized Sites for Transplantation. Invited Commentary. Transplantation (IF=3.7); 2018: 102(11), 1793-1794. https://pubmed.ncbi.nlm.nih.gov/29794938/
  20. Manzoli V, Villa C, Bayer AL, Morales LC, Molano RD, Torrente Y, Ricordi C, Hubbell JA, Tomei AA Immunoisolation of Murine Islet Allografts in Vascularized Sites Through Conformal Coating with Polyethylene Glycol. American Journal of Transplantation (IF=5.7); 2018: 18(3), 590-603. https://pubmed.ncbi.nlm.nih.gov/29068143/
  21. Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D’Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells. Transplantation (IF=3.7); 2018: 102(8), 1223-1229.
  22. Buchwald, P., Tamayo, A., Manzoli, V., Tomei AA, Stabler, C. Glucose-Stimulated Insulin Release: Parallel Perifusion Studies of Free and Hydrogel Encapsulated Human Pancreatic Islets. Biotechnology & Bioengineering (IF=4.5); 2018: 115(1), 232-245. https://pubmed.ncbi.nlm.nih.gov/28865118/
  23. Ciccocioppo R, Dos Santos CC, Baumgart DC, Cangemi GC, Cardinale V, Ciacci C, De Coppi P, Haldar D, Klersy C, Nostro MC, Ott M, Piemonti L, Tomei AA, Uygun B, Vetrano S, Orlando G. Proceedings of the signature series event of the international society for cellular therapy on "advancements in cellular therapies and regenerative medicine in digestive diseases" London, United Kingdom, May 3rd, 2017. Cytotherapy (IF=3.2); 2018: 20(3), 461-476 https://pubmed.ncbi.nlm.nih.gov/29398624/
  24. Villa C, Manzoli V, Abreu MM, Verheyen CA, Seskin M, Najjar M, Molano RD, Torrente Y, Ricordi C, Tomei AA Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice. Transplantation (IF=3.5); 2017: 101(5), 1025-1035. https://pubmed.ncbi.nlm.nih.gov/27525644/
  25. Manzoli V, Colter DC., Dhanaraj S, Fornoni A, Ricordi C., Pileggi A., Tomei AA, Engineering Human Renal Epithelial Cells for Transplantation in Regenerative Medicine. Medical Engineering & Physics (IF=2.2).; 2017 Oct: 48, 3-13. https://pubmed.ncbi.nlm.nih.gov/28416198/
  26. Tomei AA, Villa C, Ricordi C, Development of an encapsulated stem cell-based therapy for diabetes. Expert Opinion on Biological Therapy (IF=3.7), 15(9); 2015: 15(9), 1321-36. https://pubmed.ncbi.nlm.nih.gov/26156291/
  27. Najjar M, Manzoli V, Abreu M, Villa C, Martino MM, Molano RD, Torrente Y, Pileggi A, Inverardi L, Ricordi C, Hubbell JA, Tomei AA, Fibrin Gels Engineered with Pro-Angiogenic Growth Factors Promote Engraftment of Pancreatic Islets in Extrahepatic Sites in Mice. Biotechnology and Bioengineering (IF=4.5); 2015: 112(9), 1916-26. https://pubmed.ncbi.nlm.nih.gov/25786390/
  28. Tomei AA, Manzoli V, Fraker C, Giraldo JA, Velluto D, Najjar M, Pileggi A, Molano RD, Ricordi C, Stabler CL, Hubbell JA, Device design and materials optimization of conformal coating for islets of Langerhans. Proc Natl Acad Sci (IF=9.7); 2014: 111(29), 10514-9. Coverart awarded. https://pubmed.ncbi.nlm.nih.gov/24982192/
  29. Dane, K., Nembrini, C., Tomei, A., Eby, J. K., O'Neil, C. P., Velluto, D., Swartz, M. A., Inverardi, L., Hubbell, J. A. Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival. J Control Release (IF=7.7); 2011: 156(2), 154-60. https://pubmed.ncbi.nlm.nih.gov/21864593/
  30. Shields, J. D., Kourtis, I., Tomei, A., Roberts, J., Swartz, M. A. Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science (IF=37); 2010: 328(5979), 749-52. https://pubmed.ncbi.nlm.nih.gov/20339029/
  31. Tomei, A., Siegert, S., Britschgi, M. R., Luther, S. A., Swartz, M. A. Fluid Flow Regulates Stromal Cell Organization and CCL21 Expression in a Tissue-engineered Lymph Node Microenvironment. Journal of Immunology (IF=4.9); 2009: 183(7), 4273-83. https://pubmed.ncbi.nlm.nih.gov/19734211/
  32. Tomei, A., Boschetti, F., Gervaso, F., Swartz, M. A. 3D Collagen Cultures Under Well-Defined Dynamic Strain: A Novel Strain Device with a Porous Elastomeric Support. Biotechnology & Bioengineering (IF=4.5); 2009: 103(1), 217-25. https://pubmed.ncbi.nlm.nih.gov/19148875/
  33. Boschetti, F. A., Tomei, A., Turri, S., Swartz, M. A., Levi, M. Design, Fabrication and Characterization of a Composite Scaffold for Bone Tissue Engineering. International Journal of Artificial Organs (IF=1.2); 2008: 31(8), 697-707. https://pubmed.ncbi.nlm.nih.gov/18825642/
  34. Tomei, A., Choe, M. M., Swartz, M. A. Effects of Dynamic Compression on Lentiviral Transduction in an In Vitro Airway Wall Model. Am J Physiol Lung Cell Mol Physiol (IF=4.7), 2008: 294(1), L79-86. https://pubmed.ncbi.nlm.nih.gov/18024723/
  35. Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA. Autologous Chemotaxis as a Mechanism of Tumor Cell Homing to Lymphatics via Interstitial Flow and Autocrine CCR7 Signaling. Cancer Cell (IF=23.2); 2007: 11(6), 526-38. https://pubmed.ncbi.nlm.nih.gov/17560334/
  36. Tomei AA. Choe MM, Swartz MM. Physiological 3D Tissue Model of the Airway Wall and Mucosa. Nature Protocols (IF=13.3); 2006: 1(1), 357-362. https://pubmed.ncbi.nlm.nih.gov/17406256/

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